You can see a few things in the level that restrict your moves and thus lead the way to the solution.
The red block can only be matched if there are two blocks above or below it in the column before the red locked block. You can use the blue and yellow blocks for that.
Because of this you should not let the blue blocks combine before (like in the leftmost column). The red block can't go up that column either since it would be trapped, but it can't go the right way either.
This means that it has to go the left way, but it has to be stopped by other blocks (blue and yellow).
For all of this to work you might need to reorder the blocks at the beginning, use the gap above the red block for this.